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New technology at the Institute of Microbiology of the Military Medical Academy

30. 10. 2024

A new device has been installed at the Institute of Microbiology of the Military Medical Academy, which represents a major advance in the fight against antibiotic-resistant bacteria, especially important for the treatment of sepsis.
The d-RAST (Direct Rapid Antimicrobial Susceptibility Testing) device operates through an innovative combination of sensor technologies, microfluidics, and advanced algorithms, in order to quickly and accurately detect changes in bacterial activity when the sample is exposed to various antibiotics. This technology allows the determination of the minimum inhibitory concentration of antibiotics from a blood sample from a positive blood culture bottle within just seven hours, thus accelerating decisions on adequate therapy for treating patients.
Sepsis is a serious medical condition that occurs when an infection spreads into the bloodstream, and it is crucial to quickly start treatment with the appropriate antibiotic, especially due to the increasing number of cases of drug-resistant bacteria. Traditional tests for pathogen identification and antibiotic susceptibility testing can take two to three days, leading to unnecessary antibiotic use and increased drug resistance. With the help of the d-RAST device at the MMA, the time needed to obtain key diagnostic information can now be significantly reduced. In the context of the increasingly serious threat of antimicrobial resistance, devices such as the d-RAST are essential for improving patient care and reducing mortality due to sepsis. Rapid and targeted antibiotic therapy, enabled by this technology, has the potential to save lives and reduce the further emergence of resistant bacteria

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